The collision occurred at around 5:30 p.m. on Old Highway 53 in the area of J&L Market, which is located in the 6600 block, according to reports from the scene.
Radio reports indicated that the crash closed both lanes of traffic and involved three adults and a child.
Lake County Fire responded, and Northshore Fire also sent an ambulance to the scene for mutual aid. The reports indicated that three air ambulances were requested, as two of the parties had major injuries and a third had moderate to major injuries.
Two REACH and one CalStar helicopter responded to transport the injured parties to Santa Rosa Memorial Hospital, according to reports from the scene. The Northshore Fire ambulance transported one subject to St. Helena Hospital Clearlake.
Lake County News received reports that one person involved in the crash may have fled the scene.
The names of those involved weren't immediately available. Clearlake Police did not have a report on the crash ready for release Tuesday evening.
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